Leiomyomata uteri (uterine leiomyoma/fibroid) is a neoplasm that involves the smooth muscle of the uterus (arises form the myometrium) and is the most common tumor in females. These are commonly referred to as fibroids. This is an estrogen dependent tumor (size increases with pregnancy and decreases with menopause). Leiomyoma is usually not precancerous (does not progress to malignant leiomyosarcoma), however it does present often with multiple discrete tumors that can cause uterine bleeding or result in a miscarriage.

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