Background: Women undergoing normal delivery experience pain with a variable degree. Paracetamol which is acetaminophen drug is one of the used drugs with a high safety and effectiveness against pain. Researches that addressed the potency of paracetamol as an analgesic medication in labour and cesarean sections revealed good results.
Methods: A randomized controlled study which was conducted at Algezeera and Almarwa hospital, Kasralainy hospital and Ainshams University, Egypt in the period from February 2017 till August 2018 on multigravida women undergoing normal vaginal delivery that were randomly divided into 2 groups, one received pethidine and the second received non-steroidalanti-inflammatory drugs (NSAID) (Diclofenac).
Results: The present study revealed that there was a statistically significant difference between pethidine and NSAID in VAS score after 15 minutes with better analgesic effect in pethidine group revealing a more rapid onset of action in pethidine. In the current study, there was no statistically significant difference between pethidine and NSAID in VAS score after 30 minutes, one hour, 2 hours between the 2 groups.
Conclusion: NSAID (Diclofenac) have comparable results in pain control in active phase of labour when compared to pethidine with more rapid onset of action of pethidine.
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