Lobular carcinoma in situ (LCIS) is an uncommon condition in which abnormal cells form in the milk glands (lobules) in the breast. LCIS usually doesn’t show up on mammograms. The condition is most often discovered as a result of a breast biopsy done for another reason, such as a suspicious breast lump or an abnormal mammogram Lobular carcinoma in situ (LCIS) may also be called lobular neoplasia. In this breast change, cells that look like cancer cells are growing in the milk-producing glands of the breast (called the lobules), but they don’t grow through the wall of the lobules. Lobular carcinoma in situ (LCIS) is an area (or areas) of abnormal cell growth that increases a person’s risk of developing invasive breast cancer later on in life. Lobular means that the abnormal cells start growing in the lobules, the milk-producing glands at the end of breast ducts. Carcinoma refers to any cancer that begins in the skin or other tissues that cover internal organs — such as breast tissue.

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