An endometrial biopsy is a procedure performed to obtain a small tissue sample from the lining of the uterus, called the endometrium. After the biopsy, the endometrial tissue is examined under a microscope to identify the presence of abnormal cells, or the effects of hormones on the endometrium. Other related procedures used to evaluate and treat endometrial problems include dilation and curettage (D & C), hysteroscopy, and endometrial ablation. Please see these procedures for additional information. Endometrial biopsy to take a small tissue sample from the lining of the uterus (endometrium) for study. The endometrial tissue is viewed under a microscope to look for abnormal cells. Biopsy results may show cell changes linked to hormone levels, or abnormal tissues, such as fibroids or polyps. These can lead to abnormal bleeding. Your provider can also use endometrial biopsy to check for uterine infections, such as endometritis. Your provider may also use an endometrial biopsy to check the effects of hormone therapy or to find abnormal cells or cancer. Endometrial cancer is the most common cancer of the female reproductive organs. Endometrial biopsy is no longer advised as a routine part of testing and treatment of infertility (not able to get pregnant).

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