The perimetrium (or serous coat of uterus) is the outer serosa layer of the uterus, equivalent to peritoneum. It is embrionically derived from visceral peritoneum. Perimetrium consists of superficial mesothelium, and a thin layer of loose connective tissue beneath it. The posterior surface of the uterus is completely covered by the perimetrium, but the anterior surface only partially. The perimetrium is the outermost layer of the uterus. The uterus is composed of three layers: The perimetrium, a thin external border, The myometrium, the thick and muscular middle layer, The endometrium, the inner lining that thickens and grows monthly to prepare for pregnancy. If pregnancy does not occur, the endometrium sheds during menstruation. The perimetrium may also be called the uterine serosa.
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