Equipment and techniques for office-based endometrial sampling has generally replaced the need for diagnostic dilation and curettage performed in the hospital. These techniques provide a minimally invasive option for diagnosis of endometrial cancer, hyperplasia, and other endometrial pathology. Techniques for office procedures for endometrial sampling will be reviewed here. Dilation and curettage and an overview of the diagnostic approach to endometrial evaluation for neoplasia, including both noninvasive and invasive methods. New techniques may replace direct sampling of the endometrium. These include peripheral blood sampling for circulating tumor cells or cell free DNA. Uterine lavage with molecular testing of the sample is also being investigated.
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Women's Health and Complications 