Aromatase Inhibitors

Hormone therapy drugs that lower estrogen levels in the body by blocking aromatase, an enzyme that converts other hormones into estrogen. Aromatase inhibitors are used to treat hormone-receptor positive breast cancer. Aromatase inhibitors (AIs) are a class of drugs used in the treatment of breast cancer in postmenopausal women and gynecomastia in men. They may also be used off-label to reduce estrogen conversion when using external testosterone. They may also be used for chemoprevention in high risk women. During chemo, extra fluids and steroids together with less physical activity and a yearning for sweets all combine to cause weight gain.

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